We are searching data for your request:
Upon completion, a link will appear to access the found materials.
Complete Hoffmann-La Roche synthetic route
In 1952, BASF AG began to develop an industrially applicable vitamin A synthesis. The decision to do so was made because at that time the raw materials from petrochemicals were available in-house.
In addition, it was already apparent at this point that the new area of work with the terpenoid intermediates it contained would open up economic access to other vitamins, fragrances and natural food colors. In addition, BASF had a lot of experience in dealing with ethyne and, more generally, with unsaturated organic compounds.
On the other hand, several technical processes for vitamin A synthesis had already been developed and implemented on an industrial scale. The first technical vitamin A synthesis was developed at Hoffman-La Roche, for example, in which a C14- with a C6Block is combined.